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Astrocyte and Vascular Niche

U1239 - DC2N

Research team

Inserm

Helene CASTEL
helene.castel@univ-rouen.fr

INSERM U1239
DC2N
Université Rouen Normandie
Place Emile Blondel

76821
Mont-Saint-Aignan
http://dc2n.labos.univ-rouen.fr/index.php/equipe-3

Research interest:



Composition and main activity of the Team Astrocyte and Vascular Niche

Collaborations that have resulted in joint publications with other teams of the network:

Youssef ANOUAR / U1239 - Equipe Génomique fonctionnelle et physiopathologie neuronale et neuroendocrine
David VAUDRY / U1239 - Differenciation et Communication Neuronale et Neuroendocrine
Françis EUSTACHE / U1077

Main publications over the last few years:

27715446

Coly PM,, Perzo N,, Le Joncour V,, Lecointre C,, Schouft MT,, Desrues L,, Tonon MC,, Wurtz O,, Gandolfo P,, Castel H, and Morin F,Chemotactic G protein-coupled receptors control cell migration by repressing autophagosome biogenesis. Autophagy 2016, 122344-2362.

27473044

Lange M, Heutte N, Rigal O, Noal S, Kurtz JE, Lévy C, Allouache D, Rieux C, Lefel J, Clarisse B, Veyret C, Barthélémy P, Longato N, Castel H, Eustache F, Giffard B and Joly FDecline in Cognitive Function in Older Adults With Early-Stage Breast Cancer After Adjuvant Treatment. Oncologist 2016

26853800

Melot A, Labarre A, Vanhulle C, Rondeau S, Brasseur M, Gilard V, Castel H, Marret S and Proust FNeurodevelopmental long-term outcome in children with hydrocephalus requiring neonatal surgical treatment. Neurochirurgie 2016, 6294-9.

26796573

Clavier T, Besnier E, Lefevre-Scelles A, Lanfray D, Masmoudi O, Pelletier G, Castel H, Tonon MC and Compère VIncreased Hypothalamic Levels of Endozepines, Endogenous Ligands of Benzodiazepine Receptors, in a Rat Model of Sepsis. Shock 2016, 45653-9.

26344551

Joly F, Giffard B, Rigal O, De Ruiter MB, Small BJ, Dubois M, LeFel J, Schagen SB, Ahles TA, Wefel JS, Vardy JL, Pancré V, Lange M and Castel HImpact of Cancer and Its Treatments on Cognitive Function: Advances in Research From the Paris International Cognition and Cancer Task Force Symposium and Update Since 2012. J Pain Symptom Manage 2015, 50830-41.

25597409

Lecointre C, Desrues L, Joubert JE, Perzo N,, Guichet PO, Le Joncour V, Brulé C,, Chabbert M, Leduc R, Prézeau L, Laquerrière A, Proust F,, Gandolfo P, Morin F and Castel HSignaling switch of the urotensin II vasosactive peptide GPCR: prototypic chemotaxic mechanism in glioma. Oncogene 2015, 345080-94.

25436776

Dubois M, Le Joncour V, Tonon MC, Anouar Y, Proust F, Morin F, Gandolfo P, Joly F, Hilber P and Castel HEvaluation of the impact of the cancer therapy everolimus on the central nervous system in mice. PLoS One 2014, 9e113533.

25407756

Clavier T,,,, Tonon MC,,, Foutel A, Besnier E,,,, Lefevre-Scelles A, Morin F,,, Gandolfo P,,, Tuech JJ, Quillard M, Veber B, Dureuil B, Castel H,, and Compère V,,,Increased plasma levels of endozepines, endogenous ligands of benzodiazepine receptors, during systemic inflammation: a prospective observational study. Crit Care 2014, 18633.

25183668

Brulé C, Perzo N, Joubert JE, Sainsily X, Leduc R, Castel H and Prézeau LBiased signaling regulates the pleiotropic effects of the urotensin II receptor to modulate its cellular behaviors. FASEB J 2014, 285148-62.

24891448

Jarry M, Lecointre C, Malleval C, Desrues L, Schouft MT, Lejoncour V, Liger F, Lyvinec G, Joseph B, Loaëc N, Meijer L, Honnorat J, Gandolfo P and Castel HImpact of meriolins, a new class of cyclin-dependent kinase inhibitors, on malignant glioma proliferation and neo-angiogenesis. Neuro Oncol 2014, 161484-98.

24728627

Lévêque S, Derrey S, Castel H and Proust FThe Mini Supra-orbital Approach for Cerebral Aneurysm of the Anterior Portion of the Circle of Willis. Acta Neurochir Suppl 2014, 11921-4.

24677372

Pelé J, Moreau M, Abdi H, Rodien P, Castel H and Chabbert MComparative analysis of sequence covariation methods to mine evolutionary hubs: examples from selected GPCR families. Proteins 2014, 822141-56.

24636403

Bennani O, Derrey S, Langlois O, Castel H, Laquerriere A, Freger P and Proust FBrain metastasis from renal cell carcinoma. Neurochirurgie 2014, 6012-6.

24291465

Dubois M, Lapinte N, Villier V, Lecointre C, Roy V, Tonon MC, Gandolfo P, Joly F, Hilber P and Castel HChemotherapy-induced long-term alteration of executive functions and hippocampal cell proliferation: role of glucose as adjuvant. Neuropharmacology 2014, 79234-48.

23806761

Calvacante T, Derrey S, Curey S, Langlois O, Fréger P, Gérardin E, Castel H and Proust FDistal middle cerebral artery aneurysm: A proposition of microsurgical management. Neurochirurgie 2013, 59121-7.

23750546

Chevalier A, Dubois M, Le Joncour V, Dautrey S, Lecointre C, Romieu A, Renard PY, Castel H and Sabot CSynthesis, biological evaluation, and in vivo imaging of the first camptothecin-fluorescein conjugate. Bioconjug Chem 2013, 241119-33.

23726027

Joyard Y, Le Joncour V, Castel H, Diouf CB, Bischoff L, Papamicaël C, Levacher V, Vera P and Bohn PSynthesis and biological evaluation of a novel (99m)Tc labeled 2-nitroimidazole derivative as a potential agent for imaging tumor hypoxia. Bioorg Med Chem Lett 2013, 233704-8.

23160530

Lanfray D, Arthaud S, Ouellet J, Compère V, Do Rego JL, Leprince J, Lefranc B, Castel H, Bouchard C, Monge-Roffarello B, Richard D, Pelletier G, Vaudry H, Tonon MC and Morin FGliotransmission and brain glucose sensing: critical role of endozepines. Diabetes 2013, 62801-10.

22563490

Desrues L, Lefebvre T, Lecointre C, Schouft MT, Leprince J, Compère V, Morin F, Proust F, Gandolfo P, Tonon MC and Castel HDown-regulation of GABA(A) receptor via promiscuity with the vasoactive peptide urotensin II receptor. Potential involvement in astrocyte plasticity. PLoS One 2012, 7e36319.

22300045

Chabbert M, Castel H, Pele J, Deville J, Legendre R and Rodien PEvolution of class A G-protein-coupled receptors: implications for molecular modeling. Curr Med Chem 2012, 191110-8.

21907362

Lévêque S, Derrey S, Martinaud O, Gérardin E, Langlois O, Fréger P, Hannequin D, Castel H and Proust FSuperior interhemispheric approach for midline meningioma from the anterior cranial base. Neurochirurgie 2011, 57105-13.

20219854

Compère V, Lanfray D, Castel H, Morin F, Leprince J, Dureuil B, Vaudry H, Pelletier G and Tonon MCAcute food deprivation reduces expression of diazepam-binding inhibitor, the precursor of the anorexigenic octadecaneuropeptide ODN, in mouse glial cells. J Mol Endocrinol 2010, 44295-9.

20192922

Jarry M, Diallo M, Lecointre C, Desrues L, Tokay T, Chatenet D, Leprince J, Rossi O, Vaudry H, Tonon MC, Prézeau L, Castel H and Gandolfo PThe vasoactive peptides urotensin II and urotensin II-related peptide regulate astrocyte activity through common and distinct mechanisms: involvement in cell proliferation. Biochem J 2010, 428113-24.

19493160

Lefebvre T, Gonzalez BJ, Vaudry D, Desrues L, Falluel-Morel A, Aubert N, Fournier A, Tonon MC, Vaudry H and Castel HParadoxical effect of ethanol on potassium channel currents and cell survival in cerebellar granule neurons. J Neurochem 2009, 110976-89.

Conçu par Alexis Lebon © 2008-2017  | Mentions légales